TY - JOUR
T1 - The association of maternal age with birthweight and gestational age
T2 - A cross-cohort comparison
AU - Restrepo-Méndez, María Clara
AU - Lawlor, Debbie A.
AU - Horta, Bernardo L.
AU - Matijasevich, Alicia
AU - Santos, Iná S.
AU - Menezes, Ana M B
AU - Barros, Fernando C.
AU - Victora, Cesar G.
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Background We examined the associations of maternal age with low birthweight (LBW) and preterm birth in four cohorts from a middle- and a high-income country, where the patterning of maternal age by socio-economic position (SEP) is likely to differ.Method Population-based birth cohort studies were carried out in the city of Pelotas, Brazil in 1982, 1993, and 2004, and in Avon, UK in 1991 [Avon Longitudinal Study of Parents and Children (ALSPAC)]. Adjustment for multiple indicators of SEP were applied.Results Low SEP was associated with younger age at childbearing in all cohorts, but the magnitudes of these associations were stronger in ALSPAC. Inverse associations of SEP with LBW and preterm birth were observed in all cohorts. U-shaped associations were observed between maternal age and odds of LBW in all cohorts. After adjustment for SEP, increased odds of LBW for young mothers (Conclusion Confounding by SEP explains much of the excess risk of LBW and preterm among babies born to teenage mothers as a whole, but not for mothers aged
AB - Background We examined the associations of maternal age with low birthweight (LBW) and preterm birth in four cohorts from a middle- and a high-income country, where the patterning of maternal age by socio-economic position (SEP) is likely to differ.Method Population-based birth cohort studies were carried out in the city of Pelotas, Brazil in 1982, 1993, and 2004, and in Avon, UK in 1991 [Avon Longitudinal Study of Parents and Children (ALSPAC)]. Adjustment for multiple indicators of SEP were applied.Results Low SEP was associated with younger age at childbearing in all cohorts, but the magnitudes of these associations were stronger in ALSPAC. Inverse associations of SEP with LBW and preterm birth were observed in all cohorts. U-shaped associations were observed between maternal age and odds of LBW in all cohorts. After adjustment for SEP, increased odds of LBW for young mothers (Conclusion Confounding by SEP explains much of the excess risk of LBW and preterm among babies born to teenage mothers as a whole, but not for mothers aged
KW - low birthweight infant
KW - maternal age
KW - pregnancy in adolescence
KW - preterm birth
KW - socio-economic factors
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U2 - 10.1111/ppe.12162
DO - 10.1111/ppe.12162
M3 - Article
C2 - 25405673
AN - SCOPUS:84920024061
SN - 0269-5022
VL - 29
SP - 31
EP - 40
JO - Paediatric and Perinatal Epidemiology
JF - Paediatric and Perinatal Epidemiology
IS - 1
ER -