TY - JOUR
T1 - The Association between Hypertension and Race/Ethnicity among Breast Cancer Survivors
AU - Williams, Michelle S.
AU - Beech, Bettina M.
AU - Griffith, Derek M.
AU - Thorpe, Roland J.
N1 - Funding Information:
Dr. Thorpe was supported by the National Institute on Minority Health and Health Disparities (U54MD000214). This research project also was supported by a grant from the National Heart, Lung, and Blood Institute to the University of Mississippi Medical Center (1R25HL126145-01—MPIs Beech and Norris).
Publisher Copyright:
© 2020, W. Montague Cobb-NMA Health Institute.
PY - 2020/12
Y1 - 2020/12
N2 - Purpose: Hypertension is a significant, modifiable risk factor for cardiovascular disease (CVD). African American women who are diagnosed with early-stage breast cancer have a significantly higher risk of premature death due to CVD. The purpose of this study was to examine the association between hypertension and race/ethnicity among breast cancer survivors using data from the National Health and Nutrition Examination Surveys 1999–2014. Methods: Non-Hispanic African American and non-Hispanic White women who were diagnosed with breast cancer were identified. Hypertension was defined as taking medication to treat hypertension, having a systolic blood pressure ≥ 140, or a diastolic blood pressure ≥ 90. Modified Poisson regression was performed to estimate the prevalence ratios (PR) and corresponding 95% confidence intervals (CI) for race/ethnicity, as it relates to hypertension controlling for potential confounders. Results: Of the 524 breast cancer survivors included in our study, 107 (20.4%) were African American and 417 (80.0%) were White. After adjusting for age, marital status, education, annual household income, health insurance, smoking and drinking status, physical inactivity, obesity, and diabetes, African American breast cancer survivors had a 30% higher prevalence of hypertension (PR = 1.30 [95% CI, 1.11–1.52]) than White breast cancer survivors. Conclusions: These results indicate that African American breast cancer survivors have a significantly higher risk of CVD due to hypertension even after controlling for other comorbid conditions such as diabetes and obesity.
AB - Purpose: Hypertension is a significant, modifiable risk factor for cardiovascular disease (CVD). African American women who are diagnosed with early-stage breast cancer have a significantly higher risk of premature death due to CVD. The purpose of this study was to examine the association between hypertension and race/ethnicity among breast cancer survivors using data from the National Health and Nutrition Examination Surveys 1999–2014. Methods: Non-Hispanic African American and non-Hispanic White women who were diagnosed with breast cancer were identified. Hypertension was defined as taking medication to treat hypertension, having a systolic blood pressure ≥ 140, or a diastolic blood pressure ≥ 90. Modified Poisson regression was performed to estimate the prevalence ratios (PR) and corresponding 95% confidence intervals (CI) for race/ethnicity, as it relates to hypertension controlling for potential confounders. Results: Of the 524 breast cancer survivors included in our study, 107 (20.4%) were African American and 417 (80.0%) were White. After adjusting for age, marital status, education, annual household income, health insurance, smoking and drinking status, physical inactivity, obesity, and diabetes, African American breast cancer survivors had a 30% higher prevalence of hypertension (PR = 1.30 [95% CI, 1.11–1.52]) than White breast cancer survivors. Conclusions: These results indicate that African American breast cancer survivors have a significantly higher risk of CVD due to hypertension even after controlling for other comorbid conditions such as diabetes and obesity.
KW - Breast cancer survivor
KW - Health disparities
KW - Hypertension
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U2 - 10.1007/s40615-020-00741-7
DO - 10.1007/s40615-020-00741-7
M3 - Article
C2 - 32185742
AN - SCOPUS:85082813966
SN - 2197-3792
VL - 7
SP - 1172
EP - 1177
JO - Journal of Racial and Ethnic Health Disparities
JF - Journal of Racial and Ethnic Health Disparities
IS - 6
ER -