The apoptosome at high resolution

Xinchen Teng; J. Marie Hardwick

doi:10.1016/j.cell.2010.04.015

The apoptosome at high resolution

Xinchen Teng, J. Marie Hardwick

Bloomberg School of Public Health

Research output: Contribution to journal › Short survey › peer-review

7 Scopus citations

Abstract

The mechanism by which the apoptosome activates caspases during apoptosis has been controversial. Qi et al. (2010) now present a crystal structure of a funnel-shaped octameric apoptosome complex from the nematode Caenorhabditis elegans that challenges currently held assumptions about the human apoptosome structure.

Original language	English (US)
Pages (from-to)	402-404
Number of pages	3
Journal	Cell
Volume	141
Issue number	3
DOIs	https://doi.org/10.1016/j.cell.2010.04.015
State	Published - Apr 2010

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/j.cell.2010.04.015

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title = "The apoptosome at high resolution",

abstract = "The mechanism by which the apoptosome activates caspases during apoptosis has been controversial. Qi et al. (2010) now present a crystal structure of a funnel-shaped octameric apoptosome complex from the nematode Caenorhabditis elegans that challenges currently held assumptions about the human apoptosome structure.",

author = "Xinchen Teng and Hardwick, {J. Marie}",

year = "2010",

month = apr,

doi = "10.1016/j.cell.2010.04.015",

language = "English (US)",

volume = "141",

pages = "402--404",

journal = "Cell",

issn = "0092-8674",

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T1 - The apoptosome at high resolution

AU - Teng, Xinchen

AU - Hardwick, J. Marie

PY - 2010/4

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N2 - The mechanism by which the apoptosome activates caspases during apoptosis has been controversial. Qi et al. (2010) now present a crystal structure of a funnel-shaped octameric apoptosome complex from the nematode Caenorhabditis elegans that challenges currently held assumptions about the human apoptosome structure.

AB - The mechanism by which the apoptosome activates caspases during apoptosis has been controversial. Qi et al. (2010) now present a crystal structure of a funnel-shaped octameric apoptosome complex from the nematode Caenorhabditis elegans that challenges currently held assumptions about the human apoptosome structure.

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U2 - 10.1016/j.cell.2010.04.015

DO - 10.1016/j.cell.2010.04.015

M3 - Short survey

C2 - 20434981

AN - SCOPUS:77952334371

SN - 0092-8674

VL - 141

SP - 402

EP - 404

JO - Cell

JF - Cell

IS - 3

ER -

The apoptosome at high resolution

Abstract

ASJC Scopus subject areas

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