Ten‐year course of schizophrenia—the Madras longitudinal study

R. Thara, M. Henrietta, A. Joseph, S. Rajkumar, W. W. Eaton

Research output: Contribution to journalArticlepeer-review

97 Scopus citations


Ninety first‐episode patients fulfilling ICD‐9 criteria for schizophrenia were followed up prospectively for 10 years. Complete assessments were possible on 76. The pattern of illness was good in 67% of the cases, and the commonest patterns was one with recurrent episodes. Predictors of poor course and longer time spent in psychosis were identified. All positive and negative symptoms showed a steep decline at the end of 10 years. The results are discussed in the context of longitudinal research on the course of schizophrenia in developing countries.

Original languageEnglish (US)
Pages (from-to)329-336
Number of pages8
JournalActa Psychiatrica Scandinavica
Issue number5
StatePublished - Nov 1994
Externally publishedYes


  • longitudinal study
  • prediction
  • schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health


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