Technology innovation for infectious diseases in the developing world

Anthony D. So, Quentin Ruiz-Esparza

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Enabling innovation and access to health technologies remains a key strategy in combating infectious diseases in low- and middle-income countries (LMICs). However, a gulf between paying markets and the endemicity of such diseases has contributed to the dearth of R&D in meeting these public health needs. While the pharmaceutical industry views emerging economies as potential new markets, most of the world's poorest bottom billion now reside in middle-income countries--a fact that has complicated tiered access arrangements. However, product development partnerships--particularly those involving academic institutions and small firms--find commercial opportunities in pursuing even neglected diseases; and a growing pharmaceutical sector in BRICS countries offers hope for an indigenous base of innovation. Such innovation will be shaped by 1) access to building blocks of knowledge; 2) strategic use of intellectual property and innovative financing to meet public health goals; 3) collaborative norms of open innovation; and 4) alternative business models, some with a double bottom line. Facing such resource constraints, LMICs are poised to develop a new, more resource-effective model of innovation that holds exciting promise in meeting the needs of global health.

Original languageEnglish (US)
Article number2
Pages (from-to)1-9
Number of pages9
JournalInfectious Diseases of Poverty
Issue number1
StatePublished - Oct 15 2012
Externally publishedYes


  • Access
  • Business model
  • Innovation
  • Open innovation
  • Open source
  • Policy
  • Public health
  • R&D
  • R&D collaboration
  • Technology

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases


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