Technetium-99m phytate as a bone marrow imaging agent: Biodistribution studies in animals: Concise communication

R. G. Hamilton, P. O. Alderson, P. A. McIntyre

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Technetium-99m phytate has been suggested as a bone-marrow imaging agent. This article compares the biodistribution of Tc-99m labeled 'bone marrow' phytate, sulfur colloid, and diphosphonate in young rats and rabbits. Autoclaved bone marrow phytate revealed significant long-base deposition, but 96% of this activity was associated with compact bone and only 4% with bone marrow. This distribution is similar to that of disphosphonate, but significantly different from that of sulfur colloid. Technetium 99m-phytate is not recommended as a bone-marrow imaging agent.

Original languageEnglish (US)
Pages (from-to)563-565
Number of pages3
JournalJournal of Nuclear Medicine
Volume18
Issue number6
StatePublished - Dec 1 1977
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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