TY - JOUR
T1 - Tec family kinases in lymphocyte signaling and function
AU - Schaeffer, Edward M.
AU - Schwartzberg, Pamela L.
PY - 2000/6/1
Y1 - 2000/6/1
N2 - The Tec kinases are required for full Ca2+ mobilization in lymphocytes. Recent data suggest that this process occurs via a multiprotein complex that includes LAT and SLP-76 in T cells and BLNK/SLP-65 in B cells. Mutational analyses have revealed critical roles for Tec kinases in lymphocyte development and function.
AB - The Tec kinases are required for full Ca2+ mobilization in lymphocytes. Recent data suggest that this process occurs via a multiprotein complex that includes LAT and SLP-76 in T cells and BLNK/SLP-65 in B cells. Mutational analyses have revealed critical roles for Tec kinases in lymphocyte development and function.
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U2 - 10.1016/S0952-7915(00)00088-1
DO - 10.1016/S0952-7915(00)00088-1
M3 - Article
C2 - 10781397
AN - SCOPUS:0034092567
SN - 0952-7915
VL - 12
SP - 282
EP - 288
JO - Current Opinion in Immunology
JF - Current Opinion in Immunology
IS - 3
ER -