TCD, MRA and MRI in acute cerebral ischemia

Alexander Y. Razumovsky, J. H. Gillard, R. N. Bryan, D. F. Hanley, S. M. Oppenheimer

Research output: Contribution to journalArticlepeer-review

62 Scopus citations


Objectives - The aim of this study was to determine accuracy of transcranial Doppler ultrasound (TCD) and compare efficacy of three non- invasive tests [TCD, magnetic resonance angiography (MRA), and magnetic resonance imaging (MRI)] in patients with acute cerebral ischemia. Material and methods - This prospective study involved 30 patients. MRI, MRA, and TCD were performed within 24 h after onset of ictus. The 2nd MRI was repeated at 48-72 h and was used as the standard for the evaluation of sensitivity and specificity of MRA, TCD, and initial MRI. Results - TCD showed a sensitivity of 96% and a specificity of 33% for recognizing abnormal cerebral blood flow velocities. MRA showed a sensitivity of 46% and a specificity of 75% for assessing intracranial vascular anatomy, while initial MRI revealed a sensitivity of 84% and a specificity of 100% for evaluation of ischemic parenchymal changes. Conclusion - Our results revealed that TCD is an accurate indicator of blood flow status and correlated well with MRI, MRA abnormalities in acute stroke.

Original languageEnglish (US)
Pages (from-to)65-76
Number of pages12
JournalActa Neurologica Scandinavica
Issue number1
StatePublished - 1999
Externally publishedYes


  • Cerebral infarction
  • Imaging
  • Magnetic resonance
  • Ultrasonics

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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