Targeted Prostate Biopsy Using 68Gallium PSMA-PET/CT for Image Guidance

Demetrios N. Simopoulos; Shyam Natarajan; Tonye A. Jones; Wolfgang P. Fendler; Anthony E. Sisk; Leonard S. Marks

doi:10.1016/j.eucr.2017.05.006

Targeted Prostate Biopsy Using ⁶⁸Gallium PSMA-PET/CT for Image Guidance

Demetrios N. Simopoulos
, Shyam Natarajan
, Tonye A. Jones
, Wolfgang P. Fendler
, Anthony E. Sisk
, Leonard S. Marks

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Prostate specific membrane antigen (PSMA) scanning is a sensitive method of prostate cancer detection. In a 71 y.o. man with a PSA of 49 (6%F), 4 negative MRI studies and 6 negative biopsies over an 8 year interval, a ⁶⁸Ga-PSMA PET/CT scan showed a PSMA-avid spot in the prostate. Using image fusion technology, the lesion was target-biopsied and Gleason 3 + 4 = 7 (cancer core length of 12 mm) was identified. This case may herald a new application for PSMA scanning and prostate cancer imaging.

Original language	English (US)
Pages (from-to)	11-14
Number of pages	4
Journal	Urology Case Reports
Volume	14
DOIs	https://doi.org/10.1016/j.eucr.2017.05.006
State	Published - Sep 2017
Externally published	Yes

Keywords

PSMA
Prostate cancer
Targeted biopsy
mpMRI

ASJC Scopus subject areas

Urology

Access to Document

10.1016/j.eucr.2017.05.006

Cite this

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title = "Targeted Prostate Biopsy Using 68Gallium PSMA-PET/CT for Image Guidance",

abstract = "Prostate specific membrane antigen (PSMA) scanning is a sensitive method of prostate cancer detection. In a 71 y.o. man with a PSA of 49 (6\%F), 4 negative MRI studies and 6 negative biopsies over an 8 year interval, a 68Ga-PSMA PET/CT scan showed a PSMA-avid spot in the prostate. Using image fusion technology, the lesion was target-biopsied and Gleason 3 + 4 = 7 (cancer core length of 12 mm) was identified. This case may herald a new application for PSMA scanning and prostate cancer imaging.",

keywords = "PSMA, Prostate cancer, Targeted biopsy, mpMRI",

author = "Simopoulos, \{Demetrios N.\} and Shyam Natarajan and Jones, \{Tonye A.\} and Fendler, \{Wolfgang P.\} and Sisk, \{Anthony E.\} and Marks, \{Leonard S.\}",

note = "Publisher Copyright: {\textcopyright} 2017 The Authors",

year = "2017",

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AU - Simopoulos, Demetrios N.

AU - Natarajan, Shyam

AU - Jones, Tonye A.

AU - Fendler, Wolfgang P.

AU - Sisk, Anthony E.

AU - Marks, Leonard S.

PY - 2017/9

Y1 - 2017/9

N2 - Prostate specific membrane antigen (PSMA) scanning is a sensitive method of prostate cancer detection. In a 71 y.o. man with a PSA of 49 (6%F), 4 negative MRI studies and 6 negative biopsies over an 8 year interval, a 68Ga-PSMA PET/CT scan showed a PSMA-avid spot in the prostate. Using image fusion technology, the lesion was target-biopsied and Gleason 3 + 4 = 7 (cancer core length of 12 mm) was identified. This case may herald a new application for PSMA scanning and prostate cancer imaging.

AB - Prostate specific membrane antigen (PSMA) scanning is a sensitive method of prostate cancer detection. In a 71 y.o. man with a PSA of 49 (6%F), 4 negative MRI studies and 6 negative biopsies over an 8 year interval, a 68Ga-PSMA PET/CT scan showed a PSMA-avid spot in the prostate. Using image fusion technology, the lesion was target-biopsied and Gleason 3 + 4 = 7 (cancer core length of 12 mm) was identified. This case may herald a new application for PSMA scanning and prostate cancer imaging.

KW - PSMA

KW - Prostate cancer

KW - Targeted biopsy

KW - mpMRI

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