TY - JOUR
T1 - Targeted expression of teashirt induces ectopic eyes in Drosophila
AU - Pan, Duojia
AU - Rubin, Gerald M.
PY - 1998/12/22
Y1 - 1998/12/22
N2 - teashirt was initially identified as a gene required for the specification of the trunk segments in Drosophila embryogenesis and encodes a transcription factor with zinc finger motifs. We report here that targeted expression of teashirt in imaginal discs is sufficient to induce ectopic eye formation in non-eye tissues, a phenotype similar to that produced from targeted expression of eyeless, dachshund, and eyes absent. Furthermore, teashirt and eyeless induce the expression of each other, suggesting that teashirt is part of the gene network that functions to specify eye identity.
AB - teashirt was initially identified as a gene required for the specification of the trunk segments in Drosophila embryogenesis and encodes a transcription factor with zinc finger motifs. We report here that targeted expression of teashirt in imaginal discs is sufficient to induce ectopic eye formation in non-eye tissues, a phenotype similar to that produced from targeted expression of eyeless, dachshund, and eyes absent. Furthermore, teashirt and eyeless induce the expression of each other, suggesting that teashirt is part of the gene network that functions to specify eye identity.
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U2 - 10.1073/pnas.95.26.15508
DO - 10.1073/pnas.95.26.15508
M3 - Article
C2 - 9860999
AN - SCOPUS:0032442360
SN - 0027-8424
VL - 95
SP - 15508
EP - 15512
JO - Proceedings of the National Academy of Sciences of the United States of America
JF - Proceedings of the National Academy of Sciences of the United States of America
IS - 26
ER -