@article{23dd156e6c4b41f0b579b2dc03b55056,
title = "T cells from patients with Parkinson's disease recognize α-synuclein peptides",
abstract = "Genetic studies have shown the association of Parkinson's disease with alleles of the major histocompatibility complex. Here we show that a defined set of peptides that are derived from α-synuclein, a protein aggregated in Parkinson's disease, act as antigenic epitopes displayed by these alleles and drive helper and cytotoxic T cell responses in patients with Parkinson's disease. These responses may explain the association of Parkinson's disease with specific major histocompatibility complex alleles.",
author = "David Sulzer and Alcalay, {Roy N.} and Francesca Garretti and Lucien Cote and Ellen Kanter and Julian Agin-Liebes and Christopher Liong and Curtis McMurtrey and Hildebrand, {William H.} and Xiaobo Mao and Dawson, {Valina L.} and Dawson, {Ted M.} and Carla Oseroff and John Pham and John Sidney and Dillon, {Myles B.} and Chelsea Carpenter and Daniela Weiskopf and Elizabeth Phillips and Simon Mallal and Bjoern Peters and April Frazier and {Lindestam Arlehamn}, {Cecilia S.} and Alessandro Sette",
note = "Publisher Copyright: {\textcopyright} 2017 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.",
year = "2017",
month = jun,
day = "29",
doi = "10.1038/nature22815",
language = "English (US)",
volume = "546",
pages = "656--661",
journal = "Nature",
issn = "0028-0836",
publisher = "Nature Publishing Group",
number = "7660",
}