T cell activation: The importance of methionine metabolism

Ramon I.Klein Geltink; Erika L. Pearce

doi:10.7554/eLife.47221

T cell activation: The importance of methionine metabolism

Ramon I.Klein Geltink, Erika L. Pearce

Research output: Contribution to journal › Article › peer-review

Abstract

T helper cells import the amino acid methionine to synthesize new proteins and to provide the methyl groups needed for the methylation of RNA and DNA that drives T cell proliferation and differentiation.

Original language	English (US)
Article number	e47221
Journal	eLife
Volume	8
DOIs	https://doi.org/10.7554/eLife.47221
State	Published - May 2019
Externally published	Yes

ASJC Scopus subject areas

General Neuroscience
General Immunology and Microbiology
General Biochemistry, Genetics and Molecular Biology

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10.7554/eLife.47221

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title = "T cell activation: The importance of methionine metabolism",

abstract = "T helper cells import the amino acid methionine to synthesize new proteins and to provide the methyl groups needed for the methylation of RNA and DNA that drives T cell proliferation and differentiation.",

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volume = "8",

journal = "eLife",

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T cell activation: The importance of methionine metabolism

Abstract

ASJC Scopus subject areas

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