Systems biology of polycystic kidney disease: A critical review

Luis Fernando Menezes, Gregory G. Germino

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

The proliferation and diminishing costs of 'omics' approaches have finally opened the doors for small and medium laboratories to enter the 'systems biology era'. This is a welcome evolution that requires a new framework to design, interpret, and validate studies. Here, we highlight some of the challenges, contributions, and prospects of the 'cyst-ems biology' of polycystic kidney disease.

Original languageEnglish (US)
Pages (from-to)39-52
Number of pages14
JournalWiley Interdisciplinary Reviews: Systems Biology and Medicine
Volume7
Issue number1
DOIs
StatePublished - Jan 1 2015

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology (miscellaneous)
  • Medicine (miscellaneous)

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