Systems biology of polycystic kidney disease: A critical review

Luis Fernando Menezes, Gregory G. Germino

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


The proliferation and diminishing costs of 'omics' approaches have finally opened the doors for small and medium laboratories to enter the 'systems biology era'. This is a welcome evolution that requires a new framework to design, interpret, and validate studies. Here, we highlight some of the challenges, contributions, and prospects of the 'cyst-ems biology' of polycystic kidney disease.

Original languageEnglish (US)
Pages (from-to)39-52
Number of pages14
JournalWiley Interdisciplinary Reviews: Systems Biology and Medicine
Issue number1
StatePublished - Jan 1 2015

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology (miscellaneous)
  • Medicine (miscellaneous)


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