Systemic Therapy for Squamous Cell Carcinoma of the Head and Neck

Philip Pancari, Ranee Mehra

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


The use of systemic therapy as part of curative treatment and palliation is an evolving paradigm for squamous cell cancer of the head and neck (SCCHN), which historically has been treated with local modalities. At present, the treatment armamentarium includes traditional cytotoxic therapy, targeted biological agents, and emerging immunotherapeutics. This article discusses the use of all of these systemic approaches for the curative and palliative treatment of SCCHN.

Original languageEnglish (US)
Pages (from-to)437-454
Number of pages18
JournalSurgical Oncology Clinics of North America
Issue number3
StatePublished - Jul 1 2015


  • Chemoradiation
  • Epidermal growth factor receptor
  • Platinum chemotherapy
  • Squamous cell head and neck cancer

ASJC Scopus subject areas

  • Surgery
  • Oncology


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