Systemic Absorption of Topical Steroids

Peter G. Burch, Claude J. Migeon

Research output: Contribution to journalArticlepeer-review

37 Scopus citations


To measure the extent of systemic absorption of topical steroids, urinary excretion of 17-hydroxycorticosteroids and endogenous cortisol production rates were determined in four patients during a control period and then while receiving topical steroids. During the experimental period each patient received dexamethasone 0.01%, one drop to each eye every two hours. All four patients showed a marked reduction in corticosteroid production while receiving the topical medication.

Original languageEnglish (US)
Pages (from-to)174-176
Number of pages3
JournalArchives of ophthalmology
Issue number2
StatePublished - Feb 1968
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology


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