@article{12b5270aab614195b23a3ded75826022,
title = "Systematic review of primary and booster COVID-19 sera neutralizing ability against SARS-CoV-2 omicron variant",
abstract = "Virus neutralization data using post-vaccination sera are an important tool in informing vaccine use policy decisions, however, they often pose interpretive challenges. We systematically reviewed the pre-print and published literature for neutralization studies against Omicron using sera collected after both primary and booster vaccination. We found a high proportion of post-primary vaccination sera were not responding against Omicron but boosting increased both neutralizing activity and percent of responding sera. We recommend reporting percent of responders alongside neutralization data to portray vaccine neutralization ability more accurately.",
author = "Ioannis Sitaras and Henning Jacobsen and Higdon, {Melissa M.} and Dowling, {William E.} and Naor Bar-Zeev and {Deloria Knoll}, Maria",
note = "Funding Information: We would like to acknowledge Daniel Feikin for his contribution, comments to this manuscript, and his continuous support in efforts to make the evidence useful for policy organizations such as WHO and CEPI. The authors would also like to acknowledge CEPI for funding this work. Funding Information: We would like to acknowledge Daniel Feikin for his contribution, comments to this manuscript, and his continuous support in efforts to make the evidence useful for policy organizations such as WHO and CEPI. The authors would also like to acknowledge CEPI for funding this work. Funding Information: M.M.H. reports research grants from Pfizer for unrelated work; M.D.K. reports research grants from Pfizer and Merck and consultancy fees from Merck, all for unrelated work; N.B.Z. reports research grants from Merck, from Johnson & Johnson and from Serum Institute of India, all for unrelated work; and consulting fees from Merck for unrelated work. The rest of the authors declare no competing interests. Publisher Copyright: {\textcopyright} 2022, The Author(s).",
year = "2022",
month = dec,
doi = "10.1038/s41541-022-00565-y",
language = "English (US)",
volume = "7",
journal = "npj Vaccines",
issn = "2059-0105",
publisher = "Nature Publishing Group",
number = "1",
}