Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan Africa

Laura E. Pugh, Jacob S. Roberts, Nikita Viswasam, Elizabeth Hahn, Sophia Ryan, Ghilane Turpin, Carrie E. Lyons, Stefan Baral, Bhakti Hansoti

Research output: Contribution to journalReview articlepeer-review

Abstract

Long-term adherence to antiretroviral medication continues to present as a challenge along the continuum of the HIV care cascade. HIV interventions and support programs are significantly threatened in resource-limited settings by challenges in maintaining long-term follow-up for ART adherence. We sought to complete a systematic review to comprehensively examine ART adherence and retention in care interventions in Sub-Saharan Africa and to report on the implementation of interventions in real-world settings to inform future health investments in HIV care. Interventions were grouped according to their impact on individual, community, and health-systems levels. While a vast majority of studies evaluated a combination of interventions, those studies that incorporated the community as a resource were most successful. In addition, providing education and behavior reminders proved effective and should be accompanied by community and peer efforts for best results. Multi-level interventions, such as combining individual and community-level interventions showed promising results for long term ART adherence.

Original languageEnglish (US)
Pages (from-to)1053-1060
Number of pages8
JournalJournal of Infection and Public Health
Volume15
Issue number10
DOIs
StatePublished - Oct 2022

Keywords

  • Adherence
  • Human immunodeficiency virus (HIV)
  • Sub-Saharan Africa
  • Systematic analysis

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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