Washed mitochondrial fractions from yeast catalyze the synthesis of nicotinate mononucleotide and nicotinate adenine dinucleotide from nicotinate or nicotinamide. The synthesis is stimulated 10 fold by sonic disruption of the fractions and shows an absolute requirement for ATP, 5-phosphoribosyl-1-pyrophosphate, and MgCl2.
|Original language||English (US)|
|Number of pages||5|
|Journal||Biochemical and Biophysical Research Communications|
|State||Published - May 23 1977|
ASJC Scopus subject areas
- Molecular Biology