Synthesis of 2′-deoxy-9-deaza nucleosides using heck methodology

Kartik Temburnikar, Kelin Brace, Katherine L. Seley-Radtke

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


During the synthesis of a series of 2′-deoxy-9-deaza nucleosides using Heck methodology, the necessity for a pyrrole protecting group was discovered. The results of this brief study revealed that the benzyloxymethyl (BOM) group proved optimal, and Heck coupling using Jeffery conditions increased the coupling yield significantly. The results are reported herein.

Original languageEnglish (US)
Pages (from-to)7305-7311
Number of pages7
JournalJournal of Organic Chemistry
Issue number14
StatePublished - Jul 19 2013
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry


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