Synaptic transmission at vertebrate hair cells

Paul A. Fuchs

doi:10.1016/S0959-4388(96)80058-4

Synaptic transmission at vertebrate hair cells

Paul A. Fuchs

School of Medicine

Research output: Contribution to journal › Article › peer-review

85 Scopus citations

Abstract

Mechanosensory hair cells release chemical transmitters onto associated afferent dendrites and respond to transmitters released by efferent neurons. Dihydropyridine-sensitive, voltage-gated calcium channels support transmitter release from hair cells and may be expressed preferentially at release sites. Recently, a novel subunit of the nicotinic acetylcholine receptor family, α9, was identified and found to be expressed in rat hair cells. It appears to mediate efferent inhibition via associated calcium-activated potassium channels.

Original language	English (US)
Pages (from-to)	514-519
Number of pages	6
Journal	Current Opinion in Neurobiology
Volume	6
Issue number	4
DOIs	https://doi.org/10.1016/S0959-4388(96)80058-4
State	Published - Aug 1996

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/S0959-4388(96)80058-4

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title = "Synaptic transmission at vertebrate hair cells",

abstract = "Mechanosensory hair cells release chemical transmitters onto associated afferent dendrites and respond to transmitters released by efferent neurons. Dihydropyridine-sensitive, voltage-gated calcium channels support transmitter release from hair cells and may be expressed preferentially at release sites. Recently, a novel subunit of the nicotinic acetylcholine receptor family, α9, was identified and found to be expressed in rat hair cells. It appears to mediate efferent inhibition via associated calcium-activated potassium channels.",

author = "Fuchs, {Paul A.}",

note = "Funding Information: Research in the author{\textquoteright}s laboratory was supported by grants from the National Institute on Deafness and Other Communication Disorders and from the National Organization for Hearing Research.",

year = "1996",

month = aug,

doi = "10.1016/S0959-4388(96)80058-4",

language = "English (US)",

volume = "6",

pages = "514--519",

journal = "Current Opinion in Neurobiology",

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T1 - Synaptic transmission at vertebrate hair cells

AU - Fuchs, Paul A.

N1 - Funding Information: Research in the author’s laboratory was supported by grants from the National Institute on Deafness and Other Communication Disorders and from the National Organization for Hearing Research.

PY - 1996/8

Y1 - 1996/8

N2 - Mechanosensory hair cells release chemical transmitters onto associated afferent dendrites and respond to transmitters released by efferent neurons. Dihydropyridine-sensitive, voltage-gated calcium channels support transmitter release from hair cells and may be expressed preferentially at release sites. Recently, a novel subunit of the nicotinic acetylcholine receptor family, α9, was identified and found to be expressed in rat hair cells. It appears to mediate efferent inhibition via associated calcium-activated potassium channels.

AB - Mechanosensory hair cells release chemical transmitters onto associated afferent dendrites and respond to transmitters released by efferent neurons. Dihydropyridine-sensitive, voltage-gated calcium channels support transmitter release from hair cells and may be expressed preferentially at release sites. Recently, a novel subunit of the nicotinic acetylcholine receptor family, α9, was identified and found to be expressed in rat hair cells. It appears to mediate efferent inhibition via associated calcium-activated potassium channels.

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U2 - 10.1016/S0959-4388(96)80058-4

DO - 10.1016/S0959-4388(96)80058-4

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VL - 6

SP - 514

EP - 519

JO - Current Opinion in Neurobiology

JF - Current Opinion in Neurobiology

IS - 4

ER -

Synaptic transmission at vertebrate hair cells

Abstract

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