Symptom screening among HIV-infected pregnant women is acceptable and has high negative predictive value for active tuberculosis

Amita Gupta; Aditya Chandrasekhar; Nikhil Gupte; Sandesh Patil; Ramesh Bhosale; Pradeep Sambarey; Shivahari Ghorpade; Uma Nayak; Laila Garda; Jayagowri Sastry; Renu Bharadwaj; Robert C. Bollinger

doi:10.1093/cid/cir605

Symptom screening among HIV-infected pregnant women is acceptable and has high negative predictive value for active tuberculosis

Amita Gupta
, Aditya Chandrasekhar
, Nikhil Gupte
, Sandesh Patil
, Ramesh Bhosale
, Pradeep Sambarey
, Shivahari Ghorpade
, Uma Nayak
, Laila Garda
, Jayagowri Sastry
, Renu Bharadwaj
, Robert C. Bollinger

School of Medicine

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

We evaluated tuberculosis (TB) screening among 799 human immunodeficiency virus (HIV)-infected pregnant women in India. Eleven (1.4%) had active TB. The negative predictive value of screening using cough, fever, night sweats, or weight loss was 99.3%. Tuberculin skin test and targeted chest radiography provided no substantial benefit. TB symptom screening, as recommended by the World Health Organization, is effective for ruling out TB in HIV-infected pregnant women.

Original language	English (US)
Pages (from-to)	1015-1018
Number of pages	4
Journal	Clinical Infectious Diseases
Volume	53
Issue number	10
DOIs	https://doi.org/10.1093/cid/cir605
State	Published - Nov 15 2011

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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Gupta, A., Chandrasekhar, A., Gupte, N., Patil, S., Bhosale, R., Sambarey, P., Ghorpade, S., Nayak, U., Garda, L., Sastry, J., Bharadwaj, R., & Bollinger, R. C. (2011). Symptom screening among HIV-infected pregnant women is acceptable and has high negative predictive value for active tuberculosis. Clinical Infectious Diseases, 53(10), 1015-1018. https://doi.org/10.1093/cid/cir605

Gupta, A, Chandrasekhar, A, Gupte, N, Patil, S, Bhosale, R, Sambarey, P, Ghorpade, S, Nayak, U, Garda, L, Sastry, J, Bharadwaj, R & Bollinger, RC 2011, 'Symptom screening among HIV-infected pregnant women is acceptable and has high negative predictive value for active tuberculosis', Clinical Infectious Diseases, vol. 53, no. 10, pp. 1015-1018. https://doi.org/10.1093/cid/cir605

@article{d660567d563b47d9b9fe69517ffe9b05,

title = "Symptom screening among HIV-infected pregnant women is acceptable and has high negative predictive value for active tuberculosis",

abstract = "We evaluated tuberculosis (TB) screening among 799 human immunodeficiency virus (HIV)-infected pregnant women in India. Eleven (1.4\%) had active TB. The negative predictive value of screening using cough, fever, night sweats, or weight loss was 99.3\%. Tuberculin skin test and targeted chest radiography provided no substantial benefit. TB symptom screening, as recommended by the World Health Organization, is effective for ruling out TB in HIV-infected pregnant women.",

author = "Amita Gupta and Aditya Chandrasekhar and Nikhil Gupte and Sandesh Patil and Ramesh Bhosale and Pradeep Sambarey and Shivahari Ghorpade and Uma Nayak and Laila Garda and Jayagowri Sastry and Renu Bharadwaj and Bollinger, \{Robert C.\}",

note = "Funding Information: Financial support. This work was supported by a grant from NIAID, National Institutes of Health (NIH), (grant R01 AI45462), the NIH-Fogarty International Center NIH Program of International Training Grants in Epidemiology Related to AIDS (grant D43-TW0000), the NIH Byramjee Jeejeebhoy Medical College HIV Clinical Trials Unit (grant U01 AI069497 to N. G., S. P., R. C. B., and A. G.), and the NIH-Johns Hopkins University (JHU) K12 Junior Faculty Scholars Program and JHU Clinical Scientist Award (A. G.). Potential conflicts of interest. All authors: No reported conflicts.",

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doi = "10.1093/cid/cir605",

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AU - Bhosale, Ramesh

AU - Sambarey, Pradeep

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AU - Nayak, Uma

AU - Garda, Laila

AU - Sastry, Jayagowri

AU - Bharadwaj, Renu

AU - Bollinger, Robert C.

N1 - Funding Information: Financial support. This work was supported by a grant from NIAID, National Institutes of Health (NIH), (grant R01 AI45462), the NIH-Fogarty International Center NIH Program of International Training Grants in Epidemiology Related to AIDS (grant D43-TW0000), the NIH Byramjee Jeejeebhoy Medical College HIV Clinical Trials Unit (grant U01 AI069497 to N. G., S. P., R. C. B., and A. G.), and the NIH-Johns Hopkins University (JHU) K12 Junior Faculty Scholars Program and JHU Clinical Scientist Award (A. G.). Potential conflicts of interest. All authors: No reported conflicts.

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Symptom screening among HIV-infected pregnant women is acceptable and has high negative predictive value for active tuberculosis

Abstract

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