Abstract
Sweating serves a thermoregulatory function. Both abnormal increase (hyperhidrosis) or decrease (anhidrosis, hypohydrosis) in sweat production can impair quality of life. Structural lesions of the central or peripheral sudomotor pathway may produce localized hyperhydrosis. Generalized hyperhidrosis may be secondary to neuroendocrine disorders, malignancy, infection, or toxins, including prescription drugs, and requires appropriate workup and treatment. Primary hyperhidrosis predominantly affects axillae, palms, and soles; treatment includes topical antiperspirants, systemic pharmacotherapy including anticholinergics, Botox injections, Mira Dry, and surgery. Anhidrosis may be caused by diseases or drugs. Patterns of anhidrosis delineated by thermoregulatory sweat test allow identification of the level of lesion. Recently autobody-mediated and steroid-responsive anhidrosis have been reported.
Original language | English (US) |
---|---|
Title of host publication | The Curated Reference Collection in Neuroscience and Biobehavioral Psychology |
Publisher | Elsevier Science Ltd. |
Pages | 359-362 |
Number of pages | 4 |
ISBN (Electronic) | 9780128093245 |
DOIs | |
State | Published - Jan 1 2016 |
Externally published | Yes |
Keywords
- Anhidrosis
- Anticholinergics
- Botulinum toxin
- Hyperhidrosis
- Mira dry
- Steroid responsiveness
- Sweat patterns
- Sympathectomy
ASJC Scopus subject areas
- General Medicine