Supranuclear gaze palsy and opsoclonus after Diazinon poisoning

Tsao Wei Liang, L. J. Balcer, D. Solomon, S. R. Messé, S. L. Galetta

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


A 52 year old man developed a supranuclear gaze palsy and opsoclonus after Diazinon poisoning. The diagnosis was confirmed by low plasma and red blood cell cholinesterase activity and urine mass spectroscopy. Saccadic control may be mediated in part by acetylcholine. Opsoclonus in the setting of organophosphate intoxication may occur as a result of cholinergic excess which overactivates the fastigial nuclei.

Original languageEnglish (US)
Pages (from-to)677-679
Number of pages3
JournalJournal of Neurology Neurosurgery and Psychiatry
Issue number5
StatePublished - May 1 2003
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology
  • Psychiatry and Mental health


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