Super-achromatic rapid scanning microendoscope for ultrahigh-resolution OCT imaging

Danling Wang; Boyd V. Hunter; Michael J. Cobb; Xingde Li

doi:10.1109/JSTQE.2007.910797

Super-achromatic rapid scanning microendoscope for ultrahigh-resolution OCT imaging

Danling Wang, Boyd V. Hunter, Michael J. Cobb, Xingde Li

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Microendoscope is a critical technology to enable high-resolution imaging of internal luminal organs with optical coherence tomography. This paper reports the development of an achromatic compound microlens and a rapid scanning microendoscope based on the microlens that offers an ultrahigh transverse resolution of 4 $\mu$m (and an axial resolution of 2.2 $\mu$m when using a low-coherence light source with a broad spectrum bandwidth of 150 nm). The rapid scanning endoscope is capable of ultrahigh-resolution (UHR) optical coherence tomography (OCT) imaging in real time at an imaging speed of about 1220 lateral scans/s, with the image quality comparable to a slow bench-top UHR-OCT system ($\sim$100 scans/s). The superior performance of a scanning endoscope made of a compound microlens over an endoscope made of a conventional GRIN (gradient index) lens in imaging biological tissues has also been demonstrated.

Original language	English (US)
Pages (from-to)	1596-1601
Number of pages	6
Journal	IEEE Journal on Selected Topics in Quantum Electronics
Volume	13
Issue number	6
DOIs	https://doi.org/10.1109/JSTQE.2007.910797
State	Published - Nov 2007
Externally published	Yes

Keywords

Biomedical optical imaging
Endoscope
Optical coherence tomography (OCT)
Ultrahigh resolution (UHR) imaging

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics
Electrical and Electronic Engineering

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10.1109/JSTQE.2007.910797

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title = "Super-achromatic rapid scanning microendoscope for ultrahigh-resolution OCT imaging",

abstract = "Microendoscope is a critical technology to enable high-resolution imaging of internal luminal organs with optical coherence tomography. This paper reports the development of an achromatic compound microlens and a rapid scanning microendoscope based on the microlens that offers an ultrahigh transverse resolution of 4 $\mu$m (and an axial resolution of 2.2 $\mu$m when using a low-coherence light source with a broad spectrum bandwidth of 150 nm). The rapid scanning endoscope is capable of ultrahigh-resolution (UHR) optical coherence tomography (OCT) imaging in real time at an imaging speed of about 1220 lateral scans/s, with the image quality comparable to a slow bench-top UHR-OCT system ($\sim$100 scans/s). The superior performance of a scanning endoscope made of a compound microlens over an endoscope made of a conventional GRIN (gradient index) lens in imaging biological tissues has also been demonstrated.",

keywords = "Biomedical optical imaging, Endoscope, Optical coherence tomography (OCT), Ultrahigh resolution (UHR) imaging",

author = "Danling Wang and Hunter, {Boyd V.} and Cobb, {Michael J.} and Xingde Li",

note = "Funding Information: Manuscript received September 20, 2007. This work was supported in part by the National Institutes of Health under Grant EB-003284 and Grant CA110239 and in part by the National Science Foundation (Career Award XDL) under Grant BES-0348720.",

year = "2007",

month = nov,

doi = "10.1109/JSTQE.2007.910797",

language = "English (US)",

volume = "13",

pages = "1596--1601",

journal = "IEEE Journal on Selected Topics in Quantum Electronics",

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AU - Wang, Danling

AU - Hunter, Boyd V.

AU - Cobb, Michael J.

AU - Li, Xingde

N1 - Funding Information: Manuscript received September 20, 2007. This work was supported in part by the National Institutes of Health under Grant EB-003284 and Grant CA110239 and in part by the National Science Foundation (Career Award XDL) under Grant BES-0348720.

PY - 2007/11

Y1 - 2007/11

N2 - Microendoscope is a critical technology to enable high-resolution imaging of internal luminal organs with optical coherence tomography. This paper reports the development of an achromatic compound microlens and a rapid scanning microendoscope based on the microlens that offers an ultrahigh transverse resolution of 4 $\mu$m (and an axial resolution of 2.2 $\mu$m when using a low-coherence light source with a broad spectrum bandwidth of 150 nm). The rapid scanning endoscope is capable of ultrahigh-resolution (UHR) optical coherence tomography (OCT) imaging in real time at an imaging speed of about 1220 lateral scans/s, with the image quality comparable to a slow bench-top UHR-OCT system ($\sim$100 scans/s). The superior performance of a scanning endoscope made of a compound microlens over an endoscope made of a conventional GRIN (gradient index) lens in imaging biological tissues has also been demonstrated.

AB - Microendoscope is a critical technology to enable high-resolution imaging of internal luminal organs with optical coherence tomography. This paper reports the development of an achromatic compound microlens and a rapid scanning microendoscope based on the microlens that offers an ultrahigh transverse resolution of 4 $\mu$m (and an axial resolution of 2.2 $\mu$m when using a low-coherence light source with a broad spectrum bandwidth of 150 nm). The rapid scanning endoscope is capable of ultrahigh-resolution (UHR) optical coherence tomography (OCT) imaging in real time at an imaging speed of about 1220 lateral scans/s, with the image quality comparable to a slow bench-top UHR-OCT system ($\sim$100 scans/s). The superior performance of a scanning endoscope made of a compound microlens over an endoscope made of a conventional GRIN (gradient index) lens in imaging biological tissues has also been demonstrated.

KW - Biomedical optical imaging

KW - Endoscope

KW - Optical coherence tomography (OCT)

KW - Ultrahigh resolution (UHR) imaging

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Super-achromatic rapid scanning microendoscope for ultrahigh-resolution OCT imaging

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Keywords

ASJC Scopus subject areas

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