TY - JOUR
T1 - Suicidality, aggression, and other treatment considerations among pregnant, substance-dependent women with posttraumatic stress disorder
AU - Eggleston, A. Meade
AU - Calhoun, Patrick S.
AU - Svikis, Dace S.
AU - Tuten, Michelle
AU - Chisolm, Margaret S.
AU - Jones, Hendree E.
N1 - Funding Information:
This research was partially supported by National Institute on Drug Abuse grants P50 DA09258 and F31 DA05980 and a Dissertation Research Award from the American Psychological Association. We are sincerely grateful to the Johns Hopkins University School of Medicine and the staff of the Center for Addiction and Pregnancy located on the Johns Hopkins Bayview Medical Center Campus for the completion of this study.
PY - 2009/9
Y1 - 2009/9
N2 - Posttraumatic stress disorder (PTSD) and other Axis I comorbidity among women with substance use disorders (SUDs) appear similarly prevalent and are associated with comparable negative clinical profiles and treatment outcomes. The relative contribution of comorbid PTSD vs other Axis I psychiatric disorders to clinical characteristics is largely unexamined, however, despite theory and empirical data indicating that PTSD and SUDs may have a unique relationship that confers specific risk for clinical severity and poor treatment outcome. In a sample of pregnant, opioid- and/or cocaine-dependent women entering substance abuse treatment, women with PTSD (SUD-PTSD; n = 23) were compared to those with other Axis I comorbidity (SUD-PSY; n = 45) and those without Axis I comorbidity (SUD-only; n = 37). Data were collected via face-to-face interviews and urinalysis drug assays. Although the study groups had similar substance use severity, the SUD-PTSD group was more likely to report suicidality, aggression, and psychosocial impairment than both the SUD-PSY and SUD-only groups. Findings indicate treatment considerations for substance-dependent women with PTSD are broader and more severe than those with other Axis I conditions or substance dependence alone.
AB - Posttraumatic stress disorder (PTSD) and other Axis I comorbidity among women with substance use disorders (SUDs) appear similarly prevalent and are associated with comparable negative clinical profiles and treatment outcomes. The relative contribution of comorbid PTSD vs other Axis I psychiatric disorders to clinical characteristics is largely unexamined, however, despite theory and empirical data indicating that PTSD and SUDs may have a unique relationship that confers specific risk for clinical severity and poor treatment outcome. In a sample of pregnant, opioid- and/or cocaine-dependent women entering substance abuse treatment, women with PTSD (SUD-PTSD; n = 23) were compared to those with other Axis I comorbidity (SUD-PSY; n = 45) and those without Axis I comorbidity (SUD-only; n = 37). Data were collected via face-to-face interviews and urinalysis drug assays. Although the study groups had similar substance use severity, the SUD-PTSD group was more likely to report suicidality, aggression, and psychosocial impairment than both the SUD-PSY and SUD-only groups. Findings indicate treatment considerations for substance-dependent women with PTSD are broader and more severe than those with other Axis I conditions or substance dependence alone.
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U2 - 10.1016/j.comppsych.2008.11.004
DO - 10.1016/j.comppsych.2008.11.004
M3 - Article
C2 - 19683611
AN - SCOPUS:68349154315
SN - 0010-440X
VL - 50
SP - 415
EP - 423
JO - Comprehensive Psychiatry
JF - Comprehensive Psychiatry
IS - 5
ER -