TY - JOUR
T1 - Suicidal behavior in depression
T2 - Relationship to noradrenergic function
AU - Roy, Alec
AU - Pickar, David
AU - De Jong, Judith
AU - Karoum, Farouk
AU - Linnoila, Markku
PY - 1989/2/1
Y1 - 1989/2/1
N2 - We examined for relationships between suicidal behavior and noradrenergic function in depression. We compared depressed patients who had or had never attempted suicide and controls on cerebrospinal fluid, plasma, and urinary indices of noradrenergic function. There was no consistent pattern of significant findings in relationship to depressed patients who had attempted suicide. Thus, these essentially negative results suggest that the noradrenergic system is probably not a major determinant of suicidal behavior in depressed patients.
AB - We examined for relationships between suicidal behavior and noradrenergic function in depression. We compared depressed patients who had or had never attempted suicide and controls on cerebrospinal fluid, plasma, and urinary indices of noradrenergic function. There was no consistent pattern of significant findings in relationship to depressed patients who had attempted suicide. Thus, these essentially negative results suggest that the noradrenergic system is probably not a major determinant of suicidal behavior in depressed patients.
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U2 - 10.1016/0006-3223(89)90181-9
DO - 10.1016/0006-3223(89)90181-9
M3 - Article
C2 - 2914156
AN - SCOPUS:0024578784
SN - 0006-3223
VL - 25
SP - 341
EP - 350
JO - Biological Psychiatry
JF - Biological Psychiatry
IS - 3
ER -