Suicidal behavior in depression: Relationship to noradrenergic function

Alec Roy, David Pickar, Judith De Jong, Farouk Karoum, Markku Linnoila

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


We examined for relationships between suicidal behavior and noradrenergic function in depression. We compared depressed patients who had or had never attempted suicide and controls on cerebrospinal fluid, plasma, and urinary indices of noradrenergic function. There was no consistent pattern of significant findings in relationship to depressed patients who had attempted suicide. Thus, these essentially negative results suggest that the noradrenergic system is probably not a major determinant of suicidal behavior in depressed patients.

Original languageEnglish (US)
Pages (from-to)341-350
Number of pages10
JournalBiological Psychiatry
Issue number3
StatePublished - Feb 1 1989
Externally publishedYes

ASJC Scopus subject areas

  • Biological Psychiatry


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