Successful treatment of Acanthamoeba rhinosinusitis in a patient with AIDS

Jean B. Nachega, P. Rombaux, B. Weynand, G. Thomas, F. Zech

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Acanthamoeba infection is a rare, difficult-to-treat, and often fatal, opportunistic parasitic infection in immunocompromised hosts, such as patients infected with HIV. We describe an aggressive nasal and sinus infection by Acanthamoeba spp. in a person with AIDS. The resolution of this Acanthamoeba infection was secondary to a multidisciplinary treatment approach involving a combination of surgery as well as high-dose amphotericin B plus 5-fluorocytosine. In the era of the HIV/AIDS pandemic, the present report underscores the need for early identification and prompt aggressive treatment to ensure successful management of this rare but potentially fatal opportunistic infection.

Original languageEnglish (US)
Pages (from-to)621-625
Number of pages5
JournalAIDS patient care and STDs
Issue number10
StatePublished - Oct 2005
Externally publishedYes

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases


Dive into the research topics of 'Successful treatment of Acanthamoeba rhinosinusitis in a patient with AIDS'. Together they form a unique fingerprint.

Cite this