Successful in utero intervention for bilateral renal agenesis

Jessica L. Bienstock, Meredith L. Birsner, Fred Coleman, Nancy A. Hueppchen

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


BACKGROUND: We report a case of bilateral renal agenesis treated with serial amnioinfusion in which the newborn survived the newborn period and was able to undergo peritoneal dialysis as a bridge to planned renal transplantation. CASE: A 34-year-old woman, gravida 1 para 0, presented at 23 1/7 weeks of gestation with a diagnosis of anhydramnios and bilateral renal agenesis. The patient underwent weekly serial amnioinfusion with the goal of improving fetal pulmonary development. At 28 weeks of gestation, the patient delivered a live newborn who required minimal respiratory support. The neonate is currently 9 months old and is undergoing daily peritoneal dialysis. CONCLUSION: Serial amnioinfusion appears to have mitigated the severe pulmonary compromise that has, in the past, led to the death of newborns with bilateral renal agenesis.

Original languageEnglish (US)
Pages (from-to)413-415
Number of pages3
JournalObstetrics and gynecology
Issue number2 PART2
StatePublished - Aug 2014

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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