Studium der diffusion im knorpel mit der "PFG" (pulsed-field-gradient)-NMR-technik

Translated title of the contribution: Study of diffusion in cartilage by the "PFG" (pulsed-field-gradient) NMR technique

L. Naji, R. Trampel, W. Ngwa, R. Knauss, J. Schiller, K. Arnold

Research output: Contribution to journalArticlepeer-review

Abstract

Since cartilage does not contain any blood vessels, diffusion is the most important transport mechanism for its supply. Although several methods are available for the measurement of diffusion, this study focuses exclusively on NMR methods. Besides the "classic" water diffusion, the diffusion behaviour of ions and polymers in cartilage is also described. In all cases, and at short observation times; diffusion is mostly determined by the water content of the sample. However, the variation of the observation time allows to obtain information also on the internal structure of cartilage. In addition, it is discussed to which extent the individual techniques allow conclusions with respect to degenerative joint diseases, and under which in vivo conditions they can be applied.

Translated title of the contributionStudy of diffusion in cartilage by the "PFG" (pulsed-field-gradient) NMR technique
Original languageGerman
Pages (from-to)179-186
Number of pages8
JournalZeitschrift fur Medizinische Physik
Volume11
Issue number3
DOIs
StatePublished - 2001
Externally publishedYes

Keywords

  • Cartilage
  • Diffusion of polymers
  • PFG NMR
  • Restricted diffusion

ASJC Scopus subject areas

  • Biophysics
  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

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