Abstract
The described method for selective sympathetic denervation of the in vivo rabbit ovary involved stripping the ovarian artery of its nerve bundles and adventitial tissue. The ovary was then entirely free of fluorescent staining adrenergic nerves. This technique was used to study the effects on ovarian denervation on HCG induced ovulation. After HCG was administered to 22 rabbits which had previously undergone unilateral ovarian denervation, the ovaries were observed for follicular maturation and rupture. Control ovaries demonstrated a mean of 5.6 stimulated follicles/ovary; denervated ovaries had a mean of 5.4. An ruptured. of 3.5 follicles/control ovary ruptured; an average of 3.1 follicles/denervated ovary suptured. Furthermore, the time course of ovulation after HCG did not differ between denervated and intact ovaries. These results indicate that HCG induced ovulation in the rabbit is not interrupted by ovarian denervation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 363-368 |
| Number of pages | 6 |
| Journal | Fertility and sterility |
| Volume | 26 |
| Issue number | 4 |
| DOIs | |
| State | Published - 1975 |
| Externally published | Yes |
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynecology