Structure-guided design of a highly selective glycogen synthase kinase-3β inhibitor: A superior neuroprotective pyrazolone showing antimania effects

Wenwen Chen, Irina N. Gaisina, Hendra Gunosewoyo, Sam A. Malekiani, Taleen Hanania, Alan P. Kozikowski

Research output: Contribution to journalArticlepeer-review

13 Scopus citations
Original languageEnglish (US)
Pages (from-to)1587-1592
Number of pages6
Issue number9
StatePublished - Sep 5 2011
Externally publishedYes


  • Bipolar disorders
  • GSK-3
  • Kinase selectivity
  • Mania
  • Neuroprotection

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Pharmacology
  • Drug Discovery
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Organic Chemistry

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