TY - JOUR
T1 - Stress thallium-201 myocardial scintigraphy for the detection of individual coronary arterial lesions in patients with and without previous myocardial infarction
AU - Rigo, Pierre
AU - Bailey, Ian K.
AU - Griffith, Lawrence S.C.
AU - Pitt, Bertram
AU - Wagner, Henry N.
AU - Becker, Lewis C.
N1 - Funding Information:
From the Cardiovascular Division. Deoartment of Medicine, and the Division of Nuclear Medicine, Departments of Medicine and Radiology, The Johns Hopkins Medical Institutions, Baltimore, Maryland. This study was supported by U.S. Public Health Service Grant P 50 HL 17655 05 from the National Heart, Lung. and Blood Instftute, National Institutes of Health, Bethesda, Maryland. Manuscript received March 31, 1980; revised rnanu-script received March 9, 1981, accepted March 12, 1981. Address for reprints: Lewis C. Becker, MD, Cardiology Division, Johns Hopkins Medical Institutions, 601 North Wolfe Street, Baltimore, Maryland 21205.
PY - 1981/8
Y1 - 1981/8
N2 - The value of stress thallium-201 scintigraphy for detecting Individual coronary arterial stenoses was analyzed in 141 patients with angio-graphically proved coronary artery disease, 101 with and 40 without a previous myocardial infarction. In patients without infarction, the sensitivity for detecting greater than 50 percent narrowing in the left anterior descending, the right and the left circumflex coronary artery was 66, 53 and 24 percent, respectively. In those with a previous infarction, the sensitivity for demonstrating disease in the artery corresponding to the site of Infarction was 100 percent for the left anterior descending, 79 percent for the right and 63 percent for the left circumflex coronary artery. In patients with a prior anterior infarction, concomitant right or left circumflex coronary arterial lesions were detected in only 1 of 12 cases, whereas in those with previous inferior or inferolateral infarction, the sensitivity for left anterior descending coronary artery disease was 69 percent. Because of the reasonably high sensitivity for detecting left anterior descending arterial disease, Irrespective of the presence and location of previous infarction, myocardial scintigraphy was useful in identifying multivessel disease in patients with a previous inferior infarction. However, because of its relative insensitivity for right or left circumflex coronary artery disease, scintigraphy proved to be a poor predictor of multivessel disease in patients with a prior anterior infarction and in patients without previous myocardial infarction.
AB - The value of stress thallium-201 scintigraphy for detecting Individual coronary arterial stenoses was analyzed in 141 patients with angio-graphically proved coronary artery disease, 101 with and 40 without a previous myocardial infarction. In patients without infarction, the sensitivity for detecting greater than 50 percent narrowing in the left anterior descending, the right and the left circumflex coronary artery was 66, 53 and 24 percent, respectively. In those with a previous infarction, the sensitivity for demonstrating disease in the artery corresponding to the site of Infarction was 100 percent for the left anterior descending, 79 percent for the right and 63 percent for the left circumflex coronary artery. In patients with a prior anterior infarction, concomitant right or left circumflex coronary arterial lesions were detected in only 1 of 12 cases, whereas in those with previous inferior or inferolateral infarction, the sensitivity for left anterior descending coronary artery disease was 69 percent. Because of the reasonably high sensitivity for detecting left anterior descending arterial disease, Irrespective of the presence and location of previous infarction, myocardial scintigraphy was useful in identifying multivessel disease in patients with a previous inferior infarction. However, because of its relative insensitivity for right or left circumflex coronary artery disease, scintigraphy proved to be a poor predictor of multivessel disease in patients with a prior anterior infarction and in patients without previous myocardial infarction.
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U2 - 10.1016/0002-9149(81)90598-1
DO - 10.1016/0002-9149(81)90598-1
M3 - Article
C2 - 7270430
AN - SCOPUS:0019511639
SN - 0002-9149
VL - 48
SP - 209
EP - 216
JO - The American journal of cardiology
JF - The American journal of cardiology
IS - 2
ER -