Stress-controlled viscoelastic tensile response of bovine cornea

B. L. Boyce, R. E. Jones, T. D. Nguyen, J. M. Grazier

Research output: Contribution to journalArticlepeer-review


The viscoelastic response of bovine corneas was characterized using in vitro load-controlled uniaxial tension experiments. Specifically, two types of tests were employed: cycled ramp tests over a range of loading rates and creep tests over a range of hold stresses. Multiple replicates of each were used to quantify natural variability as well as mean trends. A preconditioning protocol was used to obtain a unique reference state before testing and to overcome the effects of non-physiological loading. A quasi-linear viscoelastic model incorporating a representation of the microstructure of the cornea was compared to the experimental results. For low stresses and moderate durations this model compares favorably, but overall the material displays non-linearities that cannot be represented within the quasi-linear framework.

Original languageEnglish (US)
Pages (from-to)2367-2376
Number of pages10
JournalJournal of Biomechanics
Issue number11
StatePublished - 2007
Externally publishedYes


  • Bovine cornea
  • Mechanical behavior
  • Tension
  • Viscoelasticity

ASJC Scopus subject areas

  • Biophysics
  • Orthopedics and Sports Medicine
  • Biomedical Engineering
  • Rehabilitation


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