TY - JOUR
T1 - Streptococcus sanguis Survival in K-Sol
T2 - Comparison of Gentamicin and the Fluoroquinolone Antibiotics
AU - Glaros, Dean S.
AU - Nirankari, Verinder S.
AU - Baer, John C.
AU - Bauer, Sandra A.
N1 - Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
PY - 1991/4
Y1 - 1991/4
N2 - Viridans streptococci are poorly covered by gentamicin sulfate in corneal storage medium. To evaluate possible antibiotic alternatives among the newer broad-spectrum fluoroquinolone antibiotics, we compared the survival of the viridans representative Streptococcus sanguis in K-Sol with gentamicin sulfate (100 mg/L), norfloxacin (250 mg/L), ciprofloxacin lactate (250 mg/L), ofloxacin (250 mg/L), or no antibiotic. At 23°C, K-Sol with gentamicin produced a 2-log kill by 80 minutes. By comparison, only one of the others (norfloxacin) had achieved a 2-log kill by 4 hours. At 4°C, all antibiotics differed little from the control, and none was superior to gentamicin.
AB - Viridans streptococci are poorly covered by gentamicin sulfate in corneal storage medium. To evaluate possible antibiotic alternatives among the newer broad-spectrum fluoroquinolone antibiotics, we compared the survival of the viridans representative Streptococcus sanguis in K-Sol with gentamicin sulfate (100 mg/L), norfloxacin (250 mg/L), ciprofloxacin lactate (250 mg/L), ofloxacin (250 mg/L), or no antibiotic. At 23°C, K-Sol with gentamicin produced a 2-log kill by 80 minutes. By comparison, only one of the others (norfloxacin) had achieved a 2-log kill by 4 hours. At 4°C, all antibiotics differed little from the control, and none was superior to gentamicin.
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U2 - 10.1001/archopht.1991.01080040131043
DO - 10.1001/archopht.1991.01080040131043
M3 - Article
C2 - 1901486
AN - SCOPUS:0025865616
SN - 2168-6165
VL - 109
SP - 563
EP - 564
JO - JAMA Ophthalmology
JF - JAMA Ophthalmology
IS - 4
ER -