Stomach-genetic and epigenetic alterations of preneoplastic and neoplastic lesions

Stefan David; Stephen J. Meltzera

doi:10.3233/978-1-61499-024-6-493

Stomach-genetic and epigenetic alterations of preneoplastic and neoplastic lesions

Stefan David, Stephen J. Meltzera

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Gastric cancer is one of the most common neoplasias in the world and remains an important cause of cancer-related mortality. Vast resources have been invested in the study of the molecular events driving the development and progression of gastric tumors. Gastric cancer is known to result from an interaction between host and environmental factors. The present review will discuss the most how genetic and epigenetic changes contribute to gastric carcinogenesis and their potential for developing novel diagnostic and therapeutic tools.

Original language	English (US)
Title of host publication	Translational pathology of early cancer
Publisher	IOS Press
Pages	493-507
Number of pages	15
ISBN (Print)	9781614990239
DOIs	https://doi.org/10.3233/978-1-61499-024-6-493
State	Published - Mar 2012
Externally published	Yes

Keywords

Deletion
Epigenetics
Gastric cancer
Genetics
Methylation
Microsatellite Instabilitychromosomal Instability
Mutation
Oncogene
Translocation
Tumor Suppressor Gene

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
General Medicine

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10.3233/978-1-61499-024-6-493

Cite this

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AB - Gastric cancer is one of the most common neoplasias in the world and remains an important cause of cancer-related mortality. Vast resources have been invested in the study of the molecular events driving the development and progression of gastric tumors. Gastric cancer is known to result from an interaction between host and environmental factors. The present review will discuss the most how genetic and epigenetic changes contribute to gastric carcinogenesis and their potential for developing novel diagnostic and therapeutic tools.

KW - Deletion

KW - Epigenetics

KW - Gastric cancer

KW - Genetics

KW - Methylation

KW - Microsatellite Instabilitychromosomal Instability

KW - Mutation

KW - Oncogene

KW - Translocation

KW - Tumor Suppressor Gene

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SP - 493

EP - 507

BT - Translational pathology of early cancer

PB - IOS Press

ER -

Stomach-genetic and epigenetic alterations of preneoplastic and neoplastic lesions

Abstract

Keywords

ASJC Scopus subject areas

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