Still's disease, lupus-like syndrome, and silicone breast implants. A case of 'ASIA' (Shoenfeld's syndrome)

L. J. Jara, G. Medina, E. Gómez-Bañuelos, M. A. Saavedra, O. Vera-Lastra

Research output: Contribution to journalArticlepeer-review


In recent years, four conditions, siliconosis, Gulf War syndrome (GWS), macrophagic myofasciitis syndrome (MMF) and post-vaccination phenomena, were linked to a previous exposure to an adjuvant, suggesting a common denominator, and it has been proposed to incorporate comparable conditions under a common syndrome entitled Autoimmune/inflammatory Syndrome Induced by Adjuvants (ASIA). We report a case of a female who at the age of 11 years was diagnosed with Still's disease. At the age of 22 she underwent silicone breast implants and presented with a transient lupus-like syndrome. Then, at 25 years old she had a severe activation of Still's disease in association with rupture of silicone breast implants. When the prostheses were removed, the clinical picture improved. This case fulfills the criteria for ASIA and complements seven previous reports of Still's disease in association with silicone breast implants.

Original languageEnglish (US)
Pages (from-to)140-145
Number of pages6
Issue number2
StatePublished - Feb 2012
Externally publishedYes


  • 'ASIA'
  • Still's disease
  • lupus-like syndrome
  • prostheses rupture
  • silicone breast implants

ASJC Scopus subject areas

  • Rheumatology


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