Stereoselective synthesis of (3R,4S)-3-amino-4-methyl pyrrolidine

G. Jayachitra, Ravi Kumar Anchoori, B. Venkateswara Rao

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


A stereoselective approach for the synthesis of (3R,4S)-3-amino-4-methyl pyrrolidine, a part of the structure of a quinoline antibacterial compound and the naphthyridine antitumor agent, is described. The key reaction is the one-pot reduction and regioselective cyclization of azidoditosyl derivative 9 to pyrrolidine 10.

Original languageEnglish (US)
Pages (from-to)2402-2405
Number of pages4
JournalTetrahedron Asymmetry
Issue number20
StatePublished - Oct 20 2008
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry


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