Statistical Considerations in Analysis and Interpretation of Biomarker Studies

C. R. Parikh; H. Thiessen Philbrook

doi:10.1016/B978-0-12-803014-1.00002-9

Statistical Considerations in Analysis and Interpretation of Biomarker Studies

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Here we discuss traditional and emerging statistical methods for evaluating the prediction performance of biomarkers. We highlight considerations for planning a study and discuss unique statistical considerations when executing studies assessing biomarker performance including appropriate metrics to quantify biomarker-prediction performance and sample-size estimation.

Original language	English (US)
Title of host publication	Biomarkers of Kidney Disease
Publisher	Elsevier Inc.
Pages	21-32
Number of pages	12
ISBN (Print)	9780128030141
DOIs	https://doi.org/10.1016/B978-0-12-803014-1.00002-9
State	Published - Jan 1 2017
Externally published	Yes

Keywords

Accuracy
False positive rate
Incremental value
ROC curves
True positive rate

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1016/B978-0-12-803014-1.00002-9

Cite this

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title = "Statistical Considerations in Analysis and Interpretation of Biomarker Studies",

abstract = "Here we discuss traditional and emerging statistical methods for evaluating the prediction performance of biomarkers. We highlight considerations for planning a study and discuss unique statistical considerations when executing studies assessing biomarker performance including appropriate metrics to quantify biomarker-prediction performance and sample-size estimation.",

keywords = "Accuracy, False positive rate, Incremental value, ROC curves, True positive rate",

author = "Parikh, {C. R.} and {Thiessen Philbrook}, H.",

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KW - False positive rate

KW - Incremental value

KW - ROC curves

KW - True positive rate

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BT - Biomarkers of Kidney Disease

PB - Elsevier Inc.

ER -

Statistical Considerations in Analysis and Interpretation of Biomarker Studies

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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