Staging of Liver Disease. Which Option is Right for My Patient?

Harjit Bhogal, Richard K. Sterling

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


It is important to assess the stage of liver fibrosis in chronic hepatitis C to guide treatment decisions. Liver biopsy has limitations in staging fibrosis. Several blood tests, algorithms, and imaging tests have been studied as noninvasive markers to stage fibrosis in hepatitis C. In patients without suspicion for cirrhosis, 2 noninvasive methods can be used to predict presence of absence of significant liver fibrosis; however, liver biopsy remains the gold standard. It is imperative not to miss the diagnosis of cirrhosis, because this has further implications for screening of hepatocellular carcinoma and varices.

Original languageEnglish (US)
Pages (from-to)849-861
Number of pages13
JournalInfectious disease clinics of North America
Issue number4
StatePublished - Dec 2012
Externally publishedYes


  • Hepatitis C
  • Liver fibrosis
  • Noninvasive staging

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


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