Sprinting without myostatin: a genetic determinant of athletic prowess

Research output: Contribution to journalShort surveypeer-review

44 Scopus citations


Genetic studies in several species have demonstrated that myostatin (MSTN) normally functions to limit skeletal muscle mass. In a recent study, Mosher et al. reported that a mutation in the canine MSTN gene is responsible for the double-muscling phenotype seen in 'bully' whippets. Furthermore, they show that loss of even one functional MSTN allele seems to confer a competitive advantage to racing whippets, providing the first definitive evidence that loss of myostatin function can enhance athletic performance.

Original languageEnglish (US)
Pages (from-to)475-477
Number of pages3
JournalTrends in Genetics
Issue number10
StatePublished - Oct 1 2007

ASJC Scopus subject areas

  • Genetics


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