Sporadic Creutzfeldt-Jakob disease presenting as major depression

Tianrong Tim Jiang, Howard Moses, Helen Gordon, Eugene Obah

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


We describe a 68-year-old white woman who initially had symptoms of major depression and was admitted to a psychiatric hospital where she had electroconvulsive therapy. With failure of psychiatric treatment and subsequent rapidly progressive dementia, she had left frontal brain biopsy. The biopsy revealed spongiform changes, the hallmark of Creutzfeldt-Jakob disease (CJD). We report a case of sporadic CJD with unusual initial presentation of psychiatric symptoms.

Original languageEnglish (US)
Pages (from-to)807-808
Number of pages2
JournalSouthern medical journal
Issue number8
StatePublished - Aug 1999

ASJC Scopus subject areas

  • General Medicine


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