Spectral analysis of photic stimulation in migraine

Richard H. Simon, Andrew W. Zimmerman, Allan Tasman, Mahlon S. Hale

Research output: Contribution to journalArticlepeer-review

40 Scopus citations


In seeking an electrophysiologic discriminator of migraine, we applied computer technology to power spectral analysis of the EEG with photic stimulation. In 11 normal volunteers and 11 migraineurs (both classic and common) we were able to classify all migraineurs and misclassified only one normal based on the spectral analysis. The discriminator contained 5 elements: the increased driving power of migraineurs with photic stimulation at 24 flashes/sec, 34 flashes/sec, and 38 flashes/sec; and the increased power in the alpha band in both parietal and occipital leads at 20 flashes/sec. Power spectral analysis in conjunction with photic stimulation may provide the necessary data for effective discrimination of migraine from non-migraine states.

Original languageEnglish (US)
Pages (from-to)270-276
Number of pages7
JournalElectroencephalography and Clinical Neurophysiology
Issue number3
StatePublished - 1982
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)


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