Specificity of lactoferrin as an inhibitor of granulocyte-macrophage colony-stimulating activity production from fetal mouse liver cells

J. R. Zucali; H. E. Broxmeyer; J. A. Ulatowski

doi:10.1182/blood.v54.4.951.951

Specificity of lactoferrin as an inhibitor of granulocyte-macrophage colony-stimulating activity production from fetal mouse liver cells

J. R. Zucali, H. E. Broxmeyer, J. A. Ulatowski

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Fetal mouse liver cultures capable of producing both erythropoietin (Ep) and granulocyte-macrophage colony stimulating activity (GM-CSA) were used to study the specificity of lactoferrin as an inhibitor of the production of GM-CSA. Both a granulocyte-derived colony-inhibiting activity (CIA) and lactoferrin inhibited GM-CSA production while having no effect on Ep production. These results demonstrate the specificity of lactoferrin for GM-CSA production.

Original language	English (US)
Pages (from-to)	951-954
Number of pages	4
Journal	Blood
Volume	54
Issue number	4
DOIs	https://doi.org/10.1182/blood.v54.4.951.951
State	Published - 1979
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Immunology
Hematology
Cell Biology

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10.1182/blood.v54.4.951.951

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abstract = "Fetal mouse liver cultures capable of producing both erythropoietin (Ep) and granulocyte-macrophage colony stimulating activity (GM-CSA) were used to study the specificity of lactoferrin as an inhibitor of the production of GM-CSA. Both a granulocyte-derived colony-inhibiting activity (CIA) and lactoferrin inhibited GM-CSA production while having no effect on Ep production. These results demonstrate the specificity of lactoferrin for GM-CSA production.",

author = "Zucali, {J. R.} and Broxmeyer, {H. E.} and Ulatowski, {J. A.}",

year = "1979",

doi = "10.1182/blood.v54.4.951.951",

language = "English (US)",

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AU - Zucali, J. R.

AU - Broxmeyer, H. E.

AU - Ulatowski, J. A.

PY - 1979

Y1 - 1979

N2 - Fetal mouse liver cultures capable of producing both erythropoietin (Ep) and granulocyte-macrophage colony stimulating activity (GM-CSA) were used to study the specificity of lactoferrin as an inhibitor of the production of GM-CSA. Both a granulocyte-derived colony-inhibiting activity (CIA) and lactoferrin inhibited GM-CSA production while having no effect on Ep production. These results demonstrate the specificity of lactoferrin for GM-CSA production.

AB - Fetal mouse liver cultures capable of producing both erythropoietin (Ep) and granulocyte-macrophage colony stimulating activity (GM-CSA) were used to study the specificity of lactoferrin as an inhibitor of the production of GM-CSA. Both a granulocyte-derived colony-inhibiting activity (CIA) and lactoferrin inhibited GM-CSA production while having no effect on Ep production. These results demonstrate the specificity of lactoferrin for GM-CSA production.

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Specificity of lactoferrin as an inhibitor of granulocyte-macrophage colony-stimulating activity production from fetal mouse liver cells

Abstract

ASJC Scopus subject areas

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