Solitary fibrous tumor of the tongue: Report of a case with immunohistochemical and ultrastructural studies

Sang Ling Wu; Russell Vang; Fred J. Clubb; John H. Connelly

doi:10.1053/adpa.2002.33903

Solitary fibrous tumor of the tongue: Report of a case with immunohistochemical and ultrastructural studies

Sang Ling Wu, Russell Vang, Fred J. Clubb, John H. Connelly

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Solitary fibrous tumors are rare in extrapleural sites and extremely rare in the oral cavity. We report a case of a solitary fibrous tumor arising from the tongue of a 70-year-old woman. The tumor measured 1.6 cm in maximum diameter and consists of spindle-shaped cells distributed in a haphazard pattern. Immunohistochemical studies show strong positivity for CD34 and bcl-2, and weak positivity for desmin. Smooth muscle actin and S-100 protein are negative. Electron microscopy shows uniform neoplastic spindle cells with mesenchymal features. The differential diagnosis for spindle cell neoplasms in the tongue is discussed.

Original language	English (US)
Pages (from-to)	168-171
Number of pages	4
Journal	Annals of Diagnostic Pathology
Volume	6
Issue number	3
DOIs	https://doi.org/10.1053/adpa.2002.33903
State	Published - 2002
Externally published	Yes

Keywords

Immunohistochemistry
Solitary fibrous tumor
Tongue
Ultrastructure

ASJC Scopus subject areas

Pathology and Forensic Medicine

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10.1053/adpa.2002.33903

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title = "Solitary fibrous tumor of the tongue: Report of a case with immunohistochemical and ultrastructural studies",

abstract = "Solitary fibrous tumors are rare in extrapleural sites and extremely rare in the oral cavity. We report a case of a solitary fibrous tumor arising from the tongue of a 70-year-old woman. The tumor measured 1.6 cm in maximum diameter and consists of spindle-shaped cells distributed in a haphazard pattern. Immunohistochemical studies show strong positivity for CD34 and bcl-2, and weak positivity for desmin. Smooth muscle actin and S-100 protein are negative. Electron microscopy shows uniform neoplastic spindle cells with mesenchymal features. The differential diagnosis for spindle cell neoplasms in the tongue is discussed.",

keywords = "Immunohistochemistry, Solitary fibrous tumor, Tongue, Ultrastructure",

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year = "2002",

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T1 - Solitary fibrous tumor of the tongue

T2 - Report of a case with immunohistochemical and ultrastructural studies

AU - Wu, Sang Ling

AU - Vang, Russell

AU - Clubb, Fred J.

AU - Connelly, John H.

PY - 2002

Y1 - 2002

N2 - Solitary fibrous tumors are rare in extrapleural sites and extremely rare in the oral cavity. We report a case of a solitary fibrous tumor arising from the tongue of a 70-year-old woman. The tumor measured 1.6 cm in maximum diameter and consists of spindle-shaped cells distributed in a haphazard pattern. Immunohistochemical studies show strong positivity for CD34 and bcl-2, and weak positivity for desmin. Smooth muscle actin and S-100 protein are negative. Electron microscopy shows uniform neoplastic spindle cells with mesenchymal features. The differential diagnosis for spindle cell neoplasms in the tongue is discussed.

AB - Solitary fibrous tumors are rare in extrapleural sites and extremely rare in the oral cavity. We report a case of a solitary fibrous tumor arising from the tongue of a 70-year-old woman. The tumor measured 1.6 cm in maximum diameter and consists of spindle-shaped cells distributed in a haphazard pattern. Immunohistochemical studies show strong positivity for CD34 and bcl-2, and weak positivity for desmin. Smooth muscle actin and S-100 protein are negative. Electron microscopy shows uniform neoplastic spindle cells with mesenchymal features. The differential diagnosis for spindle cell neoplasms in the tongue is discussed.

KW - Immunohistochemistry

KW - Solitary fibrous tumor

KW - Tongue

KW - Ultrastructure

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SN - 1092-9134

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SP - 168

EP - 171

JO - Annals of Diagnostic Pathology

JF - Annals of Diagnostic Pathology

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ER -

Solitary fibrous tumor of the tongue: Report of a case with immunohistochemical and ultrastructural studies

Abstract

Keywords

ASJC Scopus subject areas

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