Soft Tissue Pseudosarcomas

Justin A. Bishop

Research output: Contribution to journalArticlepeer-review


Soft tissue pathology is one of the most challenging areas of diagnostic pathology, not only because of the morphologic diversity of such lesions, but also because of their rarity and pathologists' subsequent lack of exposure to these tumors. Many lesions mimic malignant mesenchymal neoplasms, collectively referred to as "pseudosarcomas." The list of proliferations that can simulate a sarcoma is extensive and heterogeneous. This review addresses malignant, nonmesenchymal neoplasms; mesenchymal neoplasms that histologically mimic sarcomas but are benign; and benign reactive soft tissue lesions that are neither neoplastic nor malignant, but have worrisome clinical and/or morphologic features.

Original languageEnglish (US)
Pages (from-to)699-719
Number of pages21
JournalSurgical Pathology Clinics
Issue number3
StatePublished - Sep 2011


  • Ancient schwannoma
  • Atypical decubital fibroplasia
  • Atypical stromal cells
  • Cellular schwannoma
  • Massive localized lymphedema
  • Nodular fasciitis
  • Papillary endothelial hyperplasia
  • Proliferative fasciitis/myositis
  • Pseudosarcomas
  • Sarcomatoid carcinoma
  • Spindle cell melanoma
  • Spindle cell/pleomorphic lipoma

ASJC Scopus subject areas

  • Surgery
  • Pathology and Forensic Medicine


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