Smoking-Cessation Interventions in People Living With HIV Infection: A Systematic Review

Gyasi Moscou-Jackson, Yvonne Commodore-Mensah, Jason Farley, Michelle DiGiacomo

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


Tobacco smoking remains a prevalent behavior in people living with HIV infection (PLWHs) and is associated with impaired immune functioning, increased cardiovascular risk, and decreased response to antiretroviral therapy. This review presents a critique and synthesis of evidence on effective smoking-cessation interventions for PLWHs. A comprehensive search identified nine peer-reviewed intervention studies published between 1989 and 2012. The highest likelihood of smoking cessation (range of odds ratios 4.33-5.6) were in two randomized controlled trial interventions using cell phone technology. Clinically significant reductions in systolic blood pressure, weight gain, and increased CD4+ T-cell count were reported in participants who ceased smoking in three of the nine studies. Overall, multistrategy smoking-cessation interventions, delivered over multiple sessions, were effective. However, the most effective interventions were tailored to the unique individual needs of PLWHs, including assessment of and intervention for polysubstance abuse and mental health issues, as well as the inclusion of access-promoting elements.

Original languageEnglish (US)
Pages (from-to)32-45
Number of pages14
JournalJournal of the Association of Nurses in AIDS Care
Issue number1
StatePublished - Jan 2014


  • AIDS
  • HIV
  • Smoking
  • Smoking cessation intervention
  • Tobacco

ASJC Scopus subject areas

  • Advanced and Specialized Nursing


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