SMART-on-FHIR implemented over i2b2

Kavishwar B. Wagholikar, Joshua C. Mandel, Jeffery G. Klann, Nich Wattanasin, Michael Mendis, Christopher G. Chute, Kenneth D. Mandl, Shawn N. Murphy

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


We have developed an interface to serve patient data from Informatics for Integrating Biology and the Bedside (i2b2) repositories in the Fast Healthcare Interoperability Resources (FHIR) format, referred to as a SMART-on-FHIR cell. The cell serves FHIR resources on a per-patient basis, and supports the "substitutable" modular third-party applications (SMART) OAuth2 specification for authorization of client applications. It is implemented as an i2b2 server plug-in, consisting of 6 modules: authentication, REST, i2b2-to-FHIR converter, resource enrichment, query engine, and cache. The source code is freely available as open source. We tested the cell by accessing resources from a test i2b2 installation, demonstrating that a SMART app can be launched from the cell that accesses patient data stored in i2b2. We successfully retrieved demographics, medications, labs, and diagnoses for test patients. The SMART-on-FHIR cell will enable i2b2 sites to provide simplified but secure data access in FHIR format, and will spur innovation and interoperability. Further, it transforms i2b2 into an apps platform.

Original languageEnglish (US)
Pages (from-to)398-402
Number of pages5
JournalJournal of the American Medical Informatics Association : JAMIA
Issue number2
StatePublished - Mar 1 2017
Externally publishedYes


  • Database management systems
  • clinical decision support
  • information storage and retrieval
  • medical informatics
  • systems integration
  • user-computer interface

ASJC Scopus subject areas

  • Health Informatics


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