TY - JOUR
T1 - Small intestinal infections
T2 - Salmonella and human immunodeficiency virus-associated enteropathy
AU - Mundy, L. M.
AU - Sears, C. L.
PY - 1993/1/1
Y1 - 1993/1/1
N2 - Salmonella gastroenteritis is an important, common, and usually self-limited illness. Problems relating to invasive salmonellosis in immunocompromised hosts, chronic carriage, and increasing antibiotic resistance have made the management of salmonella infections more complex. This article reviews salmonellosis, focusing on recent epidemiology, pathophysiology, and treatment considerations. Areas of recent investigation of mechanisms of pathogenesis, including signal transduction pathways, the role of cytokines, and the mechanisms of the heat-labile enterotoxin, are reviewed. New concepts are also considered for enteropathy associated with human immunodeficiency virus.
AB - Salmonella gastroenteritis is an important, common, and usually self-limited illness. Problems relating to invasive salmonellosis in immunocompromised hosts, chronic carriage, and increasing antibiotic resistance have made the management of salmonella infections more complex. This article reviews salmonellosis, focusing on recent epidemiology, pathophysiology, and treatment considerations. Areas of recent investigation of mechanisms of pathogenesis, including signal transduction pathways, the role of cytokines, and the mechanisms of the heat-labile enterotoxin, are reviewed. New concepts are also considered for enteropathy associated with human immunodeficiency virus.
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U2 - 10.1097/00001574-199301000-00012
DO - 10.1097/00001574-199301000-00012
M3 - Review article
AN - SCOPUS:0027467367
SN - 0267-1379
VL - 9
SP - 77
EP - 82
JO - Current opinion in gastroenterology
JF - Current opinion in gastroenterology
IS - 1
ER -