Sleep Disturbance and Nonmalignant Chronic Pain: A Comprehensive Review of the Literature

Lynette A. Menefee, Mitchell J M Cohen, Whitney R. Anderson, Karl Doghramji, Evan D. Frank, Hochang Lee

Research output: Contribution to journalArticlepeer-review

175 Scopus citations

Abstract

Sleep disturbance is an important clinical complaint for individuals with nonmalignant pain conditions. This review is a broad introduction to the literature on sleep disturbance and chronic pain conditions. The article critically reviews studies of sleep disturbance in musculoskeletal pain, arthritis, headache, and fibromyalgia. Current neurobiological hypotheses regarding the pathogenesis of sleep disturbance and chronic pain, common comorbid disorders, and pharmacologic and non-pharmacologic treatments for sleep disturbance are reviewed.

Original languageEnglish (US)
Pages (from-to)156-172
Number of pages17
JournalPain Medicine
Volume1
Issue number2
StatePublished - 2000

Keywords

  • Chronic pain
  • Sleep disorders
  • Sleep quality

ASJC Scopus subject areas

  • Clinical Neurology

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