Skin manifestations of raynaud’s phenomenon

Noëlle S. Sherber, Fredrick M. Wigley

Research output: Chapter in Book/Report/Conference proceedingChapter


Raynaud’s phenomenon presents clinically as cold mottled skin and most commonly involves the extremities. It results from vasoconstriction of the superficial thermoregulatory vessels as an exaggerated response to cold temperatures and/or to stress. It can occur primarily, without an associated autoimmune disease, or can relate to underlying rheumatic diseases such as scleroderma or mixed connective tissue disease.

Original languageEnglish (US)
Title of host publicationSkin Manifestations in Rheumatic Disease
PublisherSpringer New York
Number of pages6
ISBN (Electronic)9781461478492
ISBN (Print)9781461478485
StatePublished - Jan 1 2014

ASJC Scopus subject areas

  • General Medicine


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